Description

Benzoic Acid, 2-Amino-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl) is a high-value, multifunctional organic building block that combines a benzoic acid core with both an amino group and a boronic ester pinacol group. This unique structure makes it a critical intermediate for modern synthetic chemistry, particularly in the construction of complex molecules via cross-coupling reactions. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to construct complex, bioactive molecules for next-generation herbicides, fungicides, and insecticides.
• Material Science & OLED Development: Serves as a building block for creating organic semiconductors, light-emitting materials, and advanced polymers with specific electronic properties.
• Ligand & Catalyst Design: The boronic ester and carboxylic acid functionalities allow it to be incorporated into sophisticated ligands for metal catalysis.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and bioconjugation reagents for studying biological processes.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO laboratories.

Basic Information

Product Name	Benzoic Acid, 2-Amino-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)
CAS No.	214360-71-1
Molecular Formula	C15H22BNO4
Molecular Weight	291.15 g/mol
Synonyms	2-Amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid; 5-Borono-2-aminobenzoic acid pinacol ester; 2-Amino-5-(pinacolatoboryl)benzoic acid; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)anthranilic acid; 2-Amino-5-boronobenzoic acid pinacol ester; B-(2-Amino-5-carboxyphenyl)boronic acid pinacol ester; 214360-71-1; 2-Amino-5-(pinacolboronato)benzoic acid
EINECS	Contact for details

Quality Control

Our production of Benzoic Acid, 2-Amino-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive applications. All materials are characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.