Description

2-(4-Methoxy-2-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling efficient and selective carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries seeking to synthesize complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for constructing biaryl and heterobiaryl scaffolds prevalent in active pharmaceutical ingredients (APIs).
• Agrochemical Development: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for synthesizing electron-transport materials and emissive layer components.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Facilitates the incorporation of functional aryl units into advanced polymer backbones for specialty materials.
• Academic and Contract Research: A standard tool in research laboratories for methodology development and complex molecule synthesis.

Basic Information

Product Name	2-(4-Methoxy-2-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	214360-68-6
Molecular Formula	C14H21BO3
Molecular Weight	248.13 g/mol
Synonyms	4-Methoxy-2-methylbenzeneboronic acid pinacol ester; (4-Methoxy-2-methylphenyl)boronic acid pinacol ester; 2-Methyl-4-methoxyphenylboronic acid pinacol ester; 2-(4-Methoxy-o-tolyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Methoxy-2-methylphenylboronic acid pinacol ester; 2-Methyl-4-methoxyphenyl-Bpin
EINECS	Contact for details

Quality Control

Our 2-(4-Methoxy-2-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR and HPLC, to ensure high chemical purity and consistent performance in cross-coupling reactions. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.