Description

4-tert-Butylphenylboronic Acid, Pinacol Ester is a protected boronic acid derivative, a crucial intermediate in modern synthetic organic chemistry. Its primary value lies in its enhanced stability and handling properties compared to the free boronic acid, making it an ideal reagent for Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity building blocks for constructing complex aromatic and heteroaromatic systems.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that incorporate the 4-tert-butylphenyl moiety.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of organic electronic materials and liquid crystal compounds for displays.
• Polymer Chemistry: Employed to create functionalized monomers and polymers with specific aromatic side chains.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new C-C bond-forming methodologies.
• Ligand & Catalyst Preparation: Used in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	4-tert-Butylphenylboronic Acid, Pinacol Ester
CAS No.	214360-66-4
Molecular Formula	C₁₆H₂₅BO₂
Molecular Weight	260.18 g/mol
Synonyms	4-tert-Butylbenzeneboronic Acid Pinacol Ester; 2-(4-tert-Butylphenyl)-5,5-dimethyl-1,3,2-dioxaborinane; 4-(tert-Butyl)phenylboronic Acid Pinacol Ester; 4-tert-Butylphenylboronic Acid Pinanediol Ester (common alternate); 4-tert-Butylphenyl-Bpin; B-(4-tert-Butylphenyl)boronic Acid Pinacol Ester; Pinacol 4-tert-Butylphenylboronate; 214360-66-4
EINECS	Contact for details

Quality Control

Our 4-tert-Butylphenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR (¹H and ¹³C), and GC to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in GMP-intermediate manufacturing and high-purity research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere (argon or nitrogen) to maintain optimal purity and prevent hydrolysis.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥98.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.