Description

2-(4-Methoxy-3-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient and selective Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, active ingredient synthesis, and functional polymer development.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biphenyl or aryl-heteroaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aryl coupling steps.
• Material Science: Serves as a monomer or precursor in the development of organic electronic materials, such as OLEDs, organic photovoltaics, and conductive polymers.
• Ligand & Catalyst Development: Employed in the synthesis of novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for constructing complex molecular architectures via palladium-catalyzed cross-coupling.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, dyes, and pigments requiring precise aryl-aryl bond formation.

Basic Information

Item	Details
Product Name	2-(4-Methoxy-3-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	214360-63-1
Molecular Formula	C14H21BO3
Molecular Weight	248.13 g/mol
Synonyms	4-Methoxy-3-methylbenzeneboronic acid pinacol ester; (4-Methoxy-3-methylphenyl)boronic acid pinacol ester; 3-Methyl-4-methoxyphenylboronic acid pinacol ester; 2-(4-Methoxy-3-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4,4,5,5-Tetramethyl-2-(4-methoxy-3-methylphenyl)-1,3,2-dioxaborolane; 214360-63-1; 3-Methyl-4-methoxybenzeneboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-(4-Methoxy-3-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR (1H, 13C, 11B), and GC to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high standards, including cGMP intermediates for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.