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2,6-Dimethoxy-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine CAS NO 214360-59-5


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CAS No.:214360-59-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2,6-Dimethoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is a high-value, synthetically versatile boronic ester derivative. This compound serves as a critical building block in modern organic synthesis, enabling the formation of complex molecular architectures through efficient cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable intermediates for developing active ingredients and functional molecules.

Application

  • Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl motifs found in active pharmaceutical ingredients (APIs) and drug candidates.
  • Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific pyridine-based structures.
  • Ligand & Catalyst Development: Serves as a starting material for synthesizing sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
  • Material Science Research: Employed in the creation of organic electronic materials, such as those for OLEDs and semiconductors, where conjugated systems are crucial.
  • Chemical Biology & Proteolysis Targeting Chimeras (PROTACs): Utilized as a modular component in the synthesis of bifunctional molecules for targeted protein degradation studies.
  • Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthetic routes and scale-up projects.

Basic Information

Product Name 2,6-Dimethoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
CAS No. 214360-59-5
Molecular Formula C15H24BNO4
Molecular Weight 293.17 g/mol
Synonyms 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,6-dimethoxypyridine; 2,6-Dimethoxy-3-pyridineboronic acid pinacol ester; 2,6-Dimethoxypyridine-3-boronic acid pinacol ester; 3-Borono-2,6-dimethoxypyridine pinacol ester; Pyridine, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,6-dimethoxy-; 2,6-Dimethoxy-3-(pinacolboryl)pyridine
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Quality Control

Every batch of 2,6-Dimethoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is produced and controlled under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Assay (HPLC) ≥97.0%
Water Content (KF) ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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