Description

4-n-Methylcarboxamidophenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative, serving as a crucial synthetic intermediate in modern organic and medicinal chemistry. Its primary value lies in its stability and reactivity, making it an essential building block for constructing complex molecules via cross-coupling reactions. This compound is particularly vital for researchers and manufacturers in the pharmaceutical and agrochemical industries engaged in developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides requiring specific aryl-boronate functionalities.
• Material Science: Employed in the creation of advanced organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Chemical Synthesis: Serves as a versatile reagent for introducing the 4-(methylcarboxamido)phenyl moiety into target molecules under mild conditions.
• Bioconjugation & Probe Development: Useful in creating labeled compounds and molecular probes for biochemical and diagnostic applications.
• Catalyst & Ligand Preparation: Acts as a precursor for synthesizing specialized ligands used in homogeneous catalysis.

Basic Information

Product Name	4-n-Methylcarboxamidophenylboronic Acid, Pinacol Ester
CAS No.	214360-57-3
Molecular Formula	C15H22BNO3
Molecular Weight	275.15 g/mol
Synonyms	4-(Methoxycarbonyl)phenylboronic Acid Pinacol Ester; 4-(Methoxycarbonyl)benzeneboronic Acid Pinacol Ester; Methyl 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate; 4-Carbomethoxyphenylboronic Acid Pinacol Ester; 4-(Pinacolatoboryl)benzoic Acid Methyl Ester; Methyl 4-(Pinacolatoboryl)benzoate; CAS 214360-57-3
EINECS	Contact for details

Quality Control

Every batch of 4-n-Methylcarboxamidophenylboronic Acid, Pinacol Ester is produced and tested under strict quality management protocols to ensure consistency and high purity for research and industrial use. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.