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3-Acetylphenylboronic Acid, Pinacol Ester CAS NO 214360-49-3


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CAS No.:214360-49-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-Acetylphenylboronic Acid, Pinacol Ester is a protected boronic acid derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in its enhanced stability compared to the free boronic acid, making it an ideal reagent for Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for constructing complex organic molecules.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
  • Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific biaryl or aryl-heteroaryl structures.
  • Material Science Research: Serves as a monomer or building block for developing organic electronic materials, such as OLEDs and conductive polymers.
  • Chemical Biology & Proteomics: Employed in the development of molecular probes, sensors, and bioconjugation reagents.
  • Catalyst & Ligand Development: Acts as a starting material for synthesizing novel organoboron ligands used in asymmetric catalysis.
  • Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses serving the fine chemical and life science industries.

Basic Information

Product Name 3-Acetylphenylboronic Acid, Pinacol Ester
CAS No. 214360-49-3
Molecular Formula C14H19BO3
Molecular Weight 246.11 g/mol
Synonyms (3-Acetylphenyl)boronic acid pinacol ester; 1-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethan-1-one; 3-Acetylbenzeneboronic acid pinacol ester; 3-Acetylphenyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Acetylphenylboronic acid neopentyl glycol ester (common name variant); 3-Acetylbenzeneboronic Acid PIN; 1-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethanone
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Quality Control

Our 3-Acetylphenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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