Description

2-Cyanophenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a key building block in cross-coupling reactions, enabling the efficient construction of complex molecules. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and fine chemical synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common scaffold in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, particularly those containing biphenyl or substituted phenyl structures.
• Agrochemical Synthesis: Employed in creating advanced herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing specialized ligands used in asymmetric catalysis and material science.
• Organic Electronic Materials: Useful in the synthesis of conjugated polymers and small molecules for OLEDs, OFETs, and other optoelectronic devices.
• Chemical Biology Probes: Facilitates the labeling and study of biological systems through bioorthogonal chemistry approaches.

Basic Information

Product Name	2-Cyanophenylboronic Acid, Pinacol Ester
CAS No.	214360-48-2
Molecular Formula	C13H16BNO2
Molecular Weight	229.08 g/mol
Synonyms	2-Cyanophenylboronic Acid Pinacol Ester; (2-Cyanophenyl)boronic Acid Pinacol Ester; 2-Cyanobenzene-1-boronic Acid Pinacol Ester; 2-Cyanophenyl-1,3,2-dioxaborolane, 4,4,5,5-Tetramethyl-; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile; Pinacol (2-Cyanophenyl)boronate; 2-CN-PhBpin
EINECS	Contact for details

Quality Control

Our 2-Cyanophenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) with lot-specific data are provided to guarantee reproducible performance in sensitive synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.