Description

2-Cyanophenylboronic Acid Neopentyl Ester is a specialized organoboron building block, valued for its enhanced stability and reactivity profile compared to its boronic acid counterpart. This compound is essential for facilitating key carbon-carbon bond-forming reactions in complex synthetic pathways. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates and active ingredients.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for constructing biaryl systems, a common motif in pharmaceuticals and organic electronic materials.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of novel drug candidates, particularly those containing substituted biphenyl or heterobiaryl structures.
• Agrochemical Active Ingredient Development: Employed in the synthesis of advanced herbicides, fungicides, and insecticides requiring specific aromatic frameworks.
• Material Science Research: Serves as a precursor for creating organic ligands, polymers, and molecular components for electronic devices.
• Chemical Biology & Probe Development: Useful for tagging and modifying biomolecules in research applications due to its selective reactivity.
• Process Chemistry & Scale-up: The neopentyl ester group offers improved handling and solubility characteristics, making it suitable for optimized manufacturing processes.

Basic Information

Product Name	2-Cyanophenylboronic Acid Neopentyl Ester
CAS No.	214360-47-1
Molecular Formula	C13H16BNO2
Molecular Weight	229.09 g/mol
Synonyms	(2-Cyanophenyl)boronic Acid Neopentyl Ester; 2-Cyanobenzeneboronic Acid Neopentyl Ester; Neopentyl (2-Cyanophenyl)boronate; Boronic Acid, B-(2-Cyanophenyl)-, Neopentyl Ester; 2-Cyanophenylboronic Acid Pinacol Ester Analog; 2-Cyano-phenylboronic Acid Neopentyl Ester; (2-Cyano-phenyl)boronic Acid Neopentyl Ester
EINECS	Contact for details

Quality Control

Every batch of 2-Cyanophenylboronic Acid Neopentyl Ester is produced and tested under strict quality management protocols to ensure consistency and reliability for your synthetic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.