Description

5-Chloro-3-Fluoropicolinaldehyde is a high-purity, versatile fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it an indispensable precursor for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce functional complexity into their molecular targets.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating complex chelating ligands used in catalysis and material science.
• Functional Material Research: Employed in the synthesis of organic electronic materials and liquid crystals due to its electron-withdrawing aldehyde and halogen substituents.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom chemical synthesis and scale-up projects in fine chemical production.

Basic Information

Product Name	5-Chloro-3-Fluoropicolinaldehyde
CAS No.	214055-11-5
Molecular Formula	C₆H₃ClFNO
Molecular Weight	159.55 g/mol
Synonyms	5-Chloro-3-fluoropyridine-2-carbaldehyde; 2-Pyridinecarboxaldehyde, 5-chloro-3-fluoro-; 5-Chloro-3-fluoro-2-formylpyridine; 5-Chloro-3-fluoropicolinaldehyde; 3-Fluoro-5-chloropicolinaldehyde; 5-Chloro-3-fluoro-2-pyridinecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-Fluoropicolinaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.