Description

Lithium Triisopropyl 2-Pyridylborate is a highly versatile organoboron reagent, specifically a pyridyl-substituted borate salt, valued for its role as a critical coupling partner in advanced organic synthesis. Its primary commercial significance lies in enabling efficient carbon-carbon and carbon-heteroatom bond formation, which is essential for constructing complex molecular architectures. This compound is particularly vital for R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity building blocks for cross-coupling reactions.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for coupling with aryl and heteroaryl halides to synthesize biaryl and heterobiaryl compounds, common scaffolds in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate Synthesis: Used in the research and scale-up production of drug candidates, especially those containing pyridine or complex heterocyclic systems.
• Agrochemical Manufacturing: Employed in the synthesis of novel herbicides, fungicides, and insecticides that require specific pyridyl-boronate intermediates.
• Ligand and Catalyst Development: Serves as a precursor or building block for creating novel ligands used in catalysis and material science.
• Organic Electronic Materials: Facilitates the synthesis of conjugated organic molecules for applications in OLEDs, OFETs, and other electronic devices.
• Chemical Research & Development: A fundamental tool in academic and industrial labs for methodological development and exploring new synthetic pathways.

Basic Information

Product Name	Lithium Triisopropyl 2-Pyridylborate
CAS No.	213764-22-8
Molecular Formula	C14H23BLiN
Molecular Weight	223.09 g/mol
Synonyms	Lithium 2-Pyridyltriisopropylborate; 2-Pyridyltriisopropylboron Lithium Salt; Triisopropyl(2-pyridyl)borate Lithium Salt; Lithium (2-Pyridyl)triisopropylborate; 2-Pyridyl-B(i-Pr)3Li; Lithium Triisopropyl(2-pyridyl)borate; 2-Pyridyltriisopropylboronic Acid Lithium Salt; B-(2-Pyridyl)triisopropylborate Lithium Salt
EINECS	Contact for details

Quality Control

Every batch of Lithium Triisopropyl 2-Pyridylborate is manufactured and tested under strict quality management protocols to ensure consistency and high performance in sensitive applications. We provide comprehensive analytical data, including NMR (1H, 11B, 13C) and HPLC purity profiles, with each shipment. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, this material should be handled and stored under an inert atmosphere (argon or nitrogen) to maintain stability and purity. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
NMR Purity (1H)	Conforms
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.