Description

2-Propenal,3-(3-Fluorophenyl)-,(2Z)-(9Ci) is a specialized fluorinated α,β-unsaturated aldehyde derivative, serving as a high-value synthetic intermediate. Its core value lies in its unique molecular architecture, which combines a reactive propenal backbone with a strategically placed fluorine atom on the aromatic ring, enabling precise modifications in complex organic syntheses. This compound is essential for researchers and process chemists in the pharmaceutical and advanced materials sectors, where it is used to construct novel molecular scaffolds for drug discovery and functional materials development.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery programs.
• Agrochemical Research: Used in the development of novel fluorinated pesticides and herbicides, where the fluorine atom can enhance biological activity, metabolic stability, and membrane permeability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated organic semiconductors and liquid crystal molecules for advanced display technologies.
• Cross-Coupling Reactions: Acts as an electrophilic partner in palladium-catalyzed cross-coupling reactions (e.g., Heck reaction) to introduce the fluorophenylpropenal moiety into complex molecules.
• Polymer Functionalization: Utilized to incorporate reactive aldehyde and fluorinated aromatic groups into polymer backbones, modifying thermal and optical properties.
• Chemical Biology Probes: Employed in the design of activity-based probes and fluorogenic substrates for studying enzyme mechanisms and cellular processes.

Basic Information

Item	Details
Product Name	2-Propenal,3-(3-Fluorophenyl)-,(2Z)-(9Ci)
CAS No.	213617-52-8
Molecular Formula	C9H7FO
Molecular Weight	150.15 g/mol
Synonyms	(2Z)-3-(3-Fluorophenyl)prop-2-enal; 3-(3-Fluorophenyl)-2-propenal, (Z)-; (Z)-3-(3-Fluorophenyl)acrylaldehyde; (Z)-3-(3-Fluorophenyl)acrylic aldehyde; (Z)-3-(m-Fluorophenyl)acrolein; (Z)-3-(3-Fluorophenyl)acrolein; 3-(3-Fluorophenyl)acrylaldehyde (Z)-; (2Z)-3-(3-Fluorophenyl)acrylaldehyde
EINECS	Contact for details

Quality Control

Our 2-Propenal,3-(3-Fluorophenyl)-,(2Z)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity to oxidation and light, prolonged exposure to air or light should be avoided. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Isomeric Purity (Z-isomer)	≥ 95.0% (by HPLC or GC)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.