Description

4-Methyl-3,4-Dihydro-2H-1,4-Benzoxazine-2-Carboxylic Acid is a high-purity, synthetically valuable heterocyclic building block. This compound is a key intermediate in the research and development of novel pharmaceuticals, particularly in the synthesis of complex molecules with potential biological activity. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing advanced molecular scaffolds.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-infective drug discovery.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its benzoxazine core structure.
• Fine Chemical Synthesis: Serves as a versatile precursor for creating complex heterocyclic compounds in custom synthesis and material science.
• Academic & Institutional R&D: Employed in university and research institute laboratories for methodological studies and exploring new chemical reactions.
• Ligand and Catalyst Development: Potential use in designing novel chiral ligands or organocatalysts due to its stereogenic center and functional groups.

Basic Information

Product Name	4-Methyl-3,4-Dihydro-2H-1,4-Benzoxazine-2-Carboxylic Acid
CAS No.	212578-38-6
Molecular Formula	C10H11NO3
Molecular Weight	193.20 g/mol
Synonyms	2H-1,4-Benzoxazine-2-carboxylic acid, 3,4-dihydro-4-methyl-; 4-Methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylic acid; 4-Methyl-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid; 2-Carboxy-4-methyl-3,4-dihydro-2H-1,4-benzoxazine; (4-Methyl-3,4-dihydro-2H-1,4-benzoxazin-2-yl)formic acid
EINECS	Contact for details

Quality Control

Our 4-Methyl-3,4-Dihydro-2H-1,4-Benzoxazine-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Custom synthesis and purity grades (e.g., >98%, >99%) are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.