Description

2-(2,5-Dihydrofuran-3-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-value, advanced boronic ester building block essential for modern synthetic chemistry. This compound is a critical reagent in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional polymers.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds, crucial in synthesizing complex biaryl and heteroaryl structures for drug discovery.
• Pharmaceutical Intermediate Synthesis: Used in the research and production of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Development: Employed in creating novel herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science & Organic Electronics: Serves as a monomer or building block for synthesizing conjugated polymers used in OLEDs, organic photovoltaics, and sensors.
• Chemical Biology & Probe Development: Utilized to synthesize molecular probes and tags for studying biological processes and target engagement.
• Library Synthesis for High-Throughput Screening: Enables the rapid generation of diverse compound libraries to identify new lead structures in drug discovery campaigns.

Basic Information

Product Name	2-(2,5-Dihydrofuran-3-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	212127-80-5
Molecular Formula	C12H19BO3
Molecular Weight	222.09 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,5-dihydrofuran; 2,5-Dihydro-3-furanboronic acid pinacol ester; 2-(2,5-Dihydro-3-furanyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-(Pinacolatoboryl)-2,5-dihydrofuran; 2,5-Dihydrofuran-3-ylboronic acid pinacol ester; 3-Borono-2,5-dihydrofuran pinacol ester; 2,5-Dihydro-3-furylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-(2,5-Dihydrofuran-3-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.