Description

Ethanone, 1-[(1R,2R)-2-Phenylcyclopropyl]- (9Ci) is a high-purity chiral building block featuring a cyclopropane ring fused with an acetophenone moiety. This compound is valued for its rigid, three-dimensional structure, which is critical for modulating the biological activity and physicochemical properties of advanced pharmaceutical intermediates. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, particularly where stereochemistry is a key design parameter.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific pesticides and herbicides where the specific spatial orientation of the molecule impacts efficacy.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development of new catalytic systems for stereoselective synthesis.
• Material Science: Potential building block for specialty polymers and liquid crystals that require rigid, aromatic components.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Ethanone, 1-[(1R,2R)-2-Phenylcyclopropyl]- (9Ci)
CAS No.	212066-31-4
Molecular Formula	C11H12O
Molecular Weight	160.21 g/mol
Synonyms	(1R,2R)-2-Phenylcyclopropyl methyl ketone; 1-[(1R,2R)-2-Phenylcyclopropyl]ethanone; (1R,2R)-2-Acetyl-1-phenylcyclopropane; trans-2-Phenylcyclopropyl methyl ketone; trans-2-Acetyl-1-phenylcyclopropane; (R,R)-2-Phenylcyclopropyl methyl ketone; Chiral Phenylcyclopropyl Ketone
EINECS	Contact for details

Quality Control

Our production of Ethanone, 1-[(1R,2R)-2-Phenylcyclopropyl]- (9Ci) adheres to stringent internal quality standards to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing critical parameters such as chiral purity, chemical assay, and impurity profile. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) requirements for advanced pharmaceutical intermediates, ensuring traceability and documentation for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.