Description

4-[(Triisopropylsilyl)Oxy]Benzaldehyde is a high-value organosilicon-protected benzaldehyde derivative, serving as a critical synthetic intermediate in advanced organic chemistry. This compound is prized for its role in introducing protected phenolic aldehyde functionalities into complex molecular architectures, enabling precise chemical transformations. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-purity building blocks for sophisticated synthesis.

Application

• Pharmaceutical Intermediate: A key protected synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing phenolic aldehyde motifs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators where the triisopropylsilyl (TIPS) group provides steric protection during synthesis.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers where controlled functionalization is required.
• Peptide and Natural Product Synthesis: Facilitates the introduction of aldehyde groups into peptides and complex natural products under mild, orthogonal protection strategies.
• Chemical Biology Probes: Used to create molecular probes and tags for studying biological systems, leveraging the reactivity of the aldehyde group.

Basic Information

Product Name	4-[(Triisopropylsilyl)Oxy]Benzaldehyde
CAS No.	211617-68-4
Molecular Formula	C16H26O2Si
Molecular Weight	278.46 g/mol
Synonyms	4-(Triisopropylsilyloxy)benzaldehyde; p-(Triisopropylsilyloxy)benzaldehyde; 4-Hydroxybenzaldehyde triisopropylsilyl ether; Benzaldehyde, 4-[(triisopropylsilyl)oxy]-; TIPS-protected 4-hydroxybenzaldehyde; 4-TIPSO-Benzaldehyde; 4-Formylphenyl triisopropylsilyl ether
EINECS	Contact for details

Quality Control

Our 4-[(Triisopropylsilyl)Oxy]Benzaldehyde is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles for production, ensuring suitability for use in research and regulated industry applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.