Description

4-Diethylphosphono-(o-Methanesulfonyl)Phenol is a high-value, multi-functional organophosphorus intermediate with a unique phenolic sulfonyl structure. This compound matters for its role as a critical building block in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), enabling precise molecular modifications. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, particularly those requiring phosphonate or sulfonate functional groups for enhanced bioactivity.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, pesticides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized phosphine-based ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the development of flame retardants, polymer modifiers, and advanced organic electronic materials.
• Chemical Biology Probes: Useful for synthesizing molecular probes and inhibitors for studying enzyme mechanisms and signal transduction pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to fine chemical companies for bespoke synthesis projects and scale-up services.

Basic Information

Product Name	4-Diethylphosphono-(o-Methanesulfonyl)Phenol
CAS No.	211055-48-0
Molecular Formula	C11H17O6PS
Molecular Weight	308.28 g/mol
Synonyms	Phenol, 4-(diethylphosphinyl)-2-(methylsulfonyl)-; 2-(Methanesulfonyl)-4-(diethylphosphinyl)phenol; 4-(Diethoxyphosphinyl)-2-(methylsulfonyl)phenol; 4-Diethylphosphinyl-2-methanesulfonylphenol; (4-Hydroxy-3-methanesulfonylphenyl)diethylphosphine oxide; Diethyl(4-hydroxy-3-(methylsulfonyl)phenyl)phosphinate
EINECS	Contact for details

Quality Control

Our 4-Diethylphosphono-(o-Methanesulfonyl)Phenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.