Description

3-Aminophenylboronic Acid Pinacol Ester is a protected boronic acid derivative that serves as a crucial synthetic intermediate in modern organic chemistry. Its value lies in the dual functionality of the boronate ester group and the aromatic amine, enabling precise cross-coupling reactions and further derivatization. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing advanced small molecules and functional polymers.

Application

• Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used to construct complex molecules for crop protection agents, leveraging the boronate ester's compatibility with various coupling partners.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Functional Material Precursor: Incorporated into the synthesis of organic electronic materials, such as OLEDs and conductive polymers, where the amine group allows for further functionalization.
• Chemical Biology Probes: Utilized in the development of molecular probes and sensors due to its reactive handles for bioconjugation.
• Custom Synthesis & R&D: A versatile starting material for contract research organizations (CROs) and academic laboratories exploring new chemical entities and reaction methodologies.

Basic Information

Product Name	3-Aminophenylboronic Acid Pinacol Ester
CAS No.	210907-84-9
Molecular Formula	C12H18BNO2
Molecular Weight	219.09 g/mol
Synonyms	3-Aminobenzeneboronic Acid Pinacol Ester; (3-Aminophenyl)boronic Acid Pinacol Ester; 3-Aminophenylboronic Acid Pinanediol Ester (common alternate); 3-Aminophenyl-Bpin; 3-NH2-Ph-Bpin; B-(3-Aminophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Aminophenyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 3-Aminophenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.