Description

(Z)-5,5,5-Trifluoro-4-Phenylpent-3-En-2-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoromethyl-substituted enone structure. This compound is valued for its role as a critical building block in the synthesis of complex bioactive molecules, offering significant advantages in modulating pharmacokinetic properties. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers and advanced organic electronic materials due to its unique electronic properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and protein-ligand interactions.
• Fluorine Chemistry Building Block: An essential reagent for introducing the trifluoromethyl moiety into complex molecular architectures in synthetic organic chemistry.

Basic Information

Product Name	(Z)-5,5,5-Trifluoro-4-Phenylpent-3-En-2-One
CAS No.	210838-94-1
Molecular Formula	C11H9F3O
Molecular Weight	214.18 g/mol
Synonyms	(Z)-5,5,5-Trifluoro-4-phenylpent-3-en-2-one; (Z)-1,1,1-Trifluoro-4-phenyl-3-penten-2-one; (Z)-4-Phenyl-5,5,5-trifluoropent-3-en-2-one; (Z)-α-Benzylidene-β,β,β-trifluoroethyl methyl ketone; (Z)-β,β,β-Trifluoro-α-benzylideneacetone; (Z)-Trifluoromethyl styryl ketone; 210838-94-1; CAS 210838-94-1
EINECS	Contact for details

Quality Control

Our (Z)-5,5,5-Trifluoro-4-Phenylpent-3-En-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light sources to maintain stability and purity. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isomeric Purity (Z-Isomer)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.