Description

2-Bromo-1-(4-Morpholinophenyl)-1-Ethanone is a specialized organic building block featuring a bromoacetyl group linked to a morpholine-substituted aromatic ring. This molecular architecture makes it a valuable intermediate for the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists working in medicinal chemistry and fine chemical synthesis. The compound's reactivity profile allows for selective functionalization, enabling the creation of novel chemical entities for drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting neurological and metabolic disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new therapeutic agents.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular probes to study enzyme function and biological pathways.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce the bromoacetyl-morpholinophenyl moiety into complex molecules.
• Ligand and Catalyst Development: Potential use in the preparation of specialized ligands for catalysis or metal-organic frameworks.

Basic Information

Product Name	2-Bromo-1-(4-Morpholinophenyl)-1-Ethanone
CAS No.	210832-85-2
Molecular Formula	C12H14BrNO2
Molecular Weight	284.15 g/mol
Synonyms	2-Bromo-1-(4-morpholinophenyl)ethanone; 2-Bromo-4'-morpholinoacetophenone; 4'-Morpholino-2-bromoacetophenone; 1-(4-Morpholinophenyl)-2-bromoethanone; p-Morpholino-ω-bromoacetophenone; α-Bromo-4-morpholinoacetophenone; Ethanone, 2-bromo-1-(4-morpholinophenyl)-
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(4-Morpholinophenyl)-1-Ethanone is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity confirmation, and impurity profiles. Our standard quality commitment aligns with cGMP principles for advanced intermediates, ensuring the material is suitable for use in regulated pre-clinical and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.