Description

3-[1,3,2]Dioxaborinan-2-Yl-Phenylamine is a versatile boronic ester derivative of aniline, serving as a critical building block in modern synthetic chemistry. This compound is valued for its role in facilitating efficient carbon-carbon and carbon-heteroatom bond formation, particularly in cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing aryl amine and boronic ester functionalities.
• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a stable and reactive organoboron reagent for constructing biaryl and heterobiaryl structures central to many drug molecules.
• Agrochemical Synthesis: Used in developing novel herbicides, fungicides, and insecticides that require specific aryl-amine scaffolds.
• Material Science Research: Employed in the creation of organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology & Proteomics: Utilized as a handle for bioconjugation and in the development of molecular probes and inhibitors.
• Academic & Industrial R&D: Serves as a fundamental reagent for methodological development in organic synthesis and catalysis studies.

Basic Information

Product Name	3-[1,3,2]Dioxaborinan-2-Yl-Phenylamine
CAS No.	210775-52-3
Molecular Formula	C9H12BNO2
Molecular Weight	176.01 g/mol
Synonyms	3-Aminophenylboronic acid 1,3-propanediol ester; (3-Aminophenyl)boronic acid pinacol ester (common misnomer); 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (isomeric/common analog); 3-Boronophenylamine cyclic ester; m-Aminophenylboronic acid cyclic ester; B-(3-Aminophenyl)-1,3,2-dioxaborinane; 3-(1,3,2-Dioxaborinan-2-yl)benzenamine
EINECS	Contact for details

Quality Control

Our 3-[1,3,2]Dioxaborinan-2-Yl-Phenylamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring reliable and reproducible performance in sensitive synthetic processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.