Description

Cyclopropanecarboxylic Acid, 2-Butyl-, Methyl Ester, (1S,2S)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its unique cyclopropane ring structure and defined stereochemistry make it a valuable intermediate for constructing complex molecules with precise three-dimensional architecture. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS, antiviral, or anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the cyclopropane moiety can contribute to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Material Science Research: Investigated as a monomer or building block for specialty polymers with unique thermal or mechanical properties derived from the strained cyclopropane ring.
• Chemical Biology Probes: Employed in the synthesis of molecular probes to study enzyme mechanisms or biological pathways due to its defined stereochemistry and potential for further functionalization.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-Butyl-, Methyl Ester, (1S,2S)- (9Ci)
CAS No.	210546-53-5
Molecular Formula	C9H16O2
Molecular Weight	156.22 g/mol
Synonyms	(1S,2S)-2-Butylcyclopropanecarboxylic acid methyl ester; Methyl (1S,2S)-2-butylcyclopropanecarboxylate; (1S,2S)-Methyl 2-butylcyclopropanecarboxylate; (1S-cis)-2-Butylcyclopropanecarboxylic Acid Methyl Ester; (+)-(1S,2S)-Methyl 2-butylcyclopropanecarboxylate; trans-(+)-Methyl 2-butylcyclopropanecarboxylate
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 2-Butyl-, Methyl Ester, (1S,2S)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC and GC, to ensure high chemical and enantiomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area. For long-term storage, keep under an inert atmosphere (e.g., nitrogen or argon) at recommended temperatures between 2°C and 8°C. Keep away from strong bases and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee (1S,2S)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.