Description

3-(4-Iodo-Phenyl)-3-Trifluoromethyl-Diaziridine is a specialized diazirine-based photoaffinity labeling reagent. This compound is valued for its ability to form highly reactive carbene intermediates upon photolysis, enabling covalent cross-linking to biological targets for structural and interaction studies. It is primarily required by research institutions and pharmaceutical companies engaged in proteomics, drug discovery, and biochemical analysis.

Application

• Photoaffinity Labeling (PAL): A critical tool for mapping protein-ligand interactions, binding sites, and protein-protein interactions in biochemical research.
• Proteomics and Target Identification: Used to irreversibly tag and identify unknown protein targets of bioactive small molecules or drugs.
• Chemical Biology Probes: Incorporated into probe molecules to study enzyme mechanisms, metabolic pathways, and cellular processes.
• Material Science Surface Modification: Potential use in creating functionalized surfaces or polymers via photochemical grafting.
• Pharmaceutical R&D: Employed in early-stage drug discovery for validating drug-target engagement and understanding pharmacokinetics.

Basic Information

Product Name	3-(4-Iodo-Phenyl)-3-Trifluoromethyl-Diaziridine
CAS No.	210107-37-2
Molecular Formula	C9H6F3IN2
Molecular Weight	326.06 g/mol
Synonyms	4-Iodophenyl(trifluoromethyl)diazirine; 3-(4-Iodophenyl)-3-(trifluoromethyl)diaziridine; 3-Trifluoromethyl-3-(4-iodophenyl)diazirine; TID; 3-(p-Iodophenyl)-3-(trifluoromethyl)diazirine; Photoaffinity Labeling Reagent TID; 4-Iodo-α-(trifluoromethyl)benzenemethanediaziridine
EINECS	Contact for details

Quality Control

Our 3-(4-Iodo-Phenyl)-3-Trifluoromethyl-Diaziridine is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 quality management standards, and our processes are designed to meet the rigorous demands of chemical biology and pharmaceutical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive (store away from light). For long-term storage, consider storing under an inert atmosphere at lower temperatures (-20°C) to maximize stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Water Content (KF)	< 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.