Description

2-Chloro-6,7-Difluoro-3-Quinolinecarboxaldehyde is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique halogenated quinoline scaffold, which serves as a versatile precursor for constructing complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, antimicrobials, and anti-cancer agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the bioactivity of the difluoroquinoline core.
• Material Science Precursor: Serves as a building block for creating functionalized organic ligands and complex molecules used in advanced materials, such as organic semiconductors or metal-organic frameworks (MOFs).
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic substitution reactions due to the reactive chloro and aldehyde functional groups.
• Fluorescent Probe Development: The quinoline structure can be modified to create novel fluorophores for sensing and imaging applications in biochemical research.

Basic Information

Product Name	2-Chloro-6,7-Difluoro-3-Quinolinecarboxaldehyde
CAS No.	209909-13-7
Molecular Formula	C10H4ClF2NO
Molecular Weight	227.60 g/mol
Synonyms	2-Chloro-6,7-difluoroquinoline-3-carboxaldehyde; 2-Chloro-6,7-difluoro-3-formylquinoline; 3-Quinolinecarboxaldehyde, 2-chloro-6,7-difluoro-; 209909-13-7; 2-Chloro-6,7-difluoroquinoline-3-carbaldehyde
EINECS	Contact for details

Quality Control

Our 2-Chloro-6,7-Difluoro-3-Quinolinecarboxaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the high standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.