Description

Tf-Diol CAS NO 209861-02-9 is a specialized fluorinated diol compound, serving as a critical building block in advanced organic synthesis. Its unique trifluoromethylated structure imparts valuable properties such as enhanced metabolic stability and lipophilicity to target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially those requiring fluorinated motifs for improved bioavailability and binding affinity.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atoms contribute to increased efficacy and environmental persistence.
• Material Science: Employed in the synthesis of specialty polymers and coatings, where fluorinated diols can enhance chemical resistance, thermal stability, and surface properties.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis, facilitating the production of enantiomerically pure compounds.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research exploring new methodologies in fluoroorganic chemistry.

Basic Information

Product Name	Tf-Diol
CAS No.	209861-02-9
Molecular Formula	C9H8F3NO3
Molecular Weight	235.16 g/mol
Synonyms	2-(Trifluoromethyl)-1,3-propanediol; 2-Trifluoromethylpropane-1,3-diol; 1,3-Propanediol, 2-(trifluoromethyl)-; TFD; Trifluoromethyl Propanediol; α-(Trifluoromethyl)trimethylene Glycol; 2-(Trifluoromethyl)propane-1,3-diol
EINECS	Contact for details

Quality Control

Every batch of Tf-Diol is produced under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.