Description

2-Chloro-4-(3-Cyanophenyl)-5-Thiazolecarboxylic Acid Ethyl Ester is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a thiazole core with chloro, cyano, and ester functionalities, enabling precise molecular modifications. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other biological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Material Science: Acts as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials.
• Chemical Synthesis Building Block: Provides a versatile platform for further derivatization (e.g., hydrolysis, reduction, cross-coupling) to create diverse chemical libraries.
• Academic & Contract Research: Employed in universities and CROs for methodological studies and the exploration of new chemical reactions involving complex heterocycles.

Basic Information

Product Name	2-Chloro-4-(3-Cyanophenyl)-5-Thiazolecarboxylic Acid Ethyl Ester
CAS No.	209732-48-9
Molecular Formula	C13H9ClN2O2S
Molecular Weight	292.74 g/mol
Synonyms	Ethyl 2-Chloro-4-(3-cyanophenyl)thiazole-5-carboxylate; 2-Chloro-4-(3-cyanophenyl)-1,3-thiazole-5-carboxylic Acid Ethyl Ester; 5-Thiazolecarboxylic acid, 2-chloro-4-(3-cyanophenyl)-, ethyl ester; 209732-48-9; AKOS BRN 0972; CTK8G0335; ZB014724; NSC 405124
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(3-Cyanophenyl)-5-Thiazolecarboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.