Description

1-Prop-2-Ynyl-3-(Trifluoromethyl)-1H-Pyrazole CAS NO 208943-57-1 is a specialized pyrazole derivative characterized by a propynyl side chain and a trifluoromethyl group, offering unique reactivity and physicochemical properties. This compound is a valuable high-purity building block for advanced chemical synthesis, particularly in the development of novel active ingredients. It is primarily sought by pharmaceutical and agrochemical research organizations for creating new molecules with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve efficacy and environmental profile.
• Material Science Research: Serves as a precursor for functionalized polymers or liquid crystals, leveraging its rigid pyrazole core and fluorine content.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological systems and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	1-Prop-2-Ynyl-3-(Trifluoromethyl)-1H-Pyrazole
CAS No.	208943-57-1
Molecular Formula	C7H5F3N2
Molecular Weight	174.12 g/mol
Synonyms	3-(Trifluoromethyl)-1-(2-propynyl)-1H-pyrazole; 1-(Prop-2-yn-1-yl)-3-(trifluoromethyl)-1H-pyrazole; 1-Propargyl-3-trifluoromethylpyrazole; 1H-Pyrazole, 1-(2-propynyl)-3-(trifluoromethyl)-; 3-Trifluoromethyl-1-propargylpyrazole; 208943-57-1; 1-(Prop-2-ynyl)-3-(trifluoromethyl)pyrazole
EINECS	Contact for details

Quality Control

Our 1-Prop-2-Ynyl-3-(Trifluoromethyl)-1H-Pyrazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for research and regulated synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.