Description

3'-(Hydroxymethyl)-Biphenyl-4-Carboxaldehyde is a versatile bifunctional aromatic aldehyde, serving as a critical building block in advanced organic synthesis. This compound matters for its dual reactive sites—the aldehyde and hydroxymethyl groups—which enable precise molecular construction for high-value intermediates. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers developing active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and anti-inflammatory agent research.
• Liquid Crystal Materials: Serves as a core building block for the synthesis of advanced liquid crystal molecules used in display technologies.
• Organic Light-Emitting Diodes (OLEDs): Used in the development of electron-transport materials and host materials for OLED devices.
• Polymer Chemistry: Monomer for creating specialty polyesters, polycarbonates, and epoxy resins with tailored thermal and mechanical properties.
• Agrochemical Synthesis: Intermediate in the production of advanced herbicides and plant growth regulators.
• Cross-Coupling Reactions: Valuable substrate in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to create complex biaryl systems.
• Chiral Ligand Synthesis: Starting material for the preparation of chiral auxiliaries and ligands used in asymmetric catalysis.
• Material Science Research: Used in the development of metal-organic frameworks (MOFs) and other porous coordination polymers.

Basic Information

Product Name	3'-(Hydroxymethyl)-Biphenyl-4-Carboxaldehyde
CAS No.	208941-47-3
Molecular Formula	C14H12O2
Molecular Weight	212.24 g/mol
Synonyms	4-Formyl-3'-hydroxymethylbiphenyl; [1,1'-Biphenyl]-4-carboxaldehyde, 3'-(hydroxymethyl)-; 3'-(Hydroxymethyl)biphenyl-4-carbaldehyde; 3'-Hydroxymethyl-4'-formylbiphenyl; 4-Biphenylcarboxaldehyde, 3'-hydroxymethyl-; Biphenyl-4-carboxaldehyde, 3'-(hydroxymethyl)-; (3'-Hydroxymethyl-[1,1'-biphenyl]-4-yl)-methanol (tautomeric form); 3'-Hydroxymethyl-4-formylbiphenyl
EINECS	Contact for details

Quality Control

Our 3'-(Hydroxymethyl)-Biphenyl-4-Carboxaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure compliance with exacting industry standards. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and REACH compliance ensures a reliable and traceable supply for global markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its nature of being easily oxidized, it is recommended to store the material under an inert atmosphere (nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.