Description

(R)-Boroabu-(+)-Pinanediol is a high-value, chiral organoboron reagent where the boron atom is protected by the (+)-pinanediol ligand. This compound matters as a critical building block for the stereoselective synthesis of complex molecules, enabling the creation of single-enantiomer products with high optical purity. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for applications in asymmetric synthesis, Suzuki-Miyaura cross-coupling reactions, and the preparation of novel active pharmaceutical ingredients (APIs).

Application

• Asymmetric Synthesis: Key chiral reagent for introducing boron-containing stereocenters in the synthesis of enantiomerically pure pharmaceuticals and natural products.
• Suzuki-Miyaura Cross-Coupling: Used as a stable, air-sensitive boronic ester precursor for forming carbon-carbon bonds under palladium catalysis.
• Pharmaceutical Intermediate: Serves as a crucial intermediate in the development of novel Active Pharmaceutical Ingredients (APIs) requiring specific chirality.
• Agrochemical Research: Employed in the synthesis of chiral herbicides, fungicides, and plant growth regulators.
• Material Science: Potential building block for creating chiral organic frameworks or polymers with specific electronic or optical properties.
• Catalyst and Ligand Development: Used in the preparation of novel chiral catalysts and ligands for transition metal catalysis.

Basic Information

Product Name	(R)-Boroabu-(+)-Pinanediol
CAS No.	208521-42-0
Molecular Formula	C₁₆H₂₇BO₂
Molecular Weight	262.20 g/mol
Synonyms	(R)-4,4,5,5-Tetramethyl-2-(2-methylpropyl)-1,3,2-dioxaborolane; (R)-Boro-tert-butane pinacol ester; (R)-2-Methyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propane; (R)-Isopropylboronic acid pinacol ester; (R)-Boro-isobutane pinanediol ester; (R)-Boroabu pinanediol ester; (R)-Pinanediol isobutylboronate
EINECS	Contact for details

Quality Control

Our (R)-Boroabu-(+)-Pinanediol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is analyzed using advanced techniques including chiral HPLC, NMR spectroscopy, and titration to confirm identity, purity, and enantiomeric excess (ee). A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry place. This material is hygroscopic and easily oxidized; prolonged exposure to air, moisture, or ambient temperature will lead to decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.