Description

4-(tert-Butylaminosulphonyl)Benzeneboronic Acid is a specialized organoboron compound featuring a sulfonamide-linked tert-butylamino group, making it a valuable bifunctional building block. This boronic acid derivative is essential for modern synthetic chemistry, particularly in cross-coupling reactions where it offers enhanced stability and selectivity. It is primarily utilized by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and heterobiaryl scaffolds central to many drug molecules.
• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential therapeutic agents, including enzyme inhibitors and receptor modulators.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Employed in the creation of organic electronic materials, such as those for OLEDs and sensors, due to its conjugated structure.
• Chemical Biology & Proteomics: Acts as a handle for bioconjugation and the development of activity-based probes and affinity purification tags.
• Catalyst & Ligand Development: Useful for synthesizing novel ligands for transition metal catalysis.

Basic Information

Item	Details
Product Name	4-(tert-Butylaminosulphonyl)Benzeneboronic Acid
CAS No.	208516-15-8
Molecular Formula	C10H16BNO4S
Molecular Weight	257.12 g/mol
Synonyms	4-(N-tert-Butylsulfamoyl)benzeneboronic acid; [4-[(tert-Butylamino)sulfonyl]phenyl]boronic acid; B-[4-[(1,1-Dimethylethylamino)sulfonyl]phenyl]boronic acid; 4-(tert-Butylsulfamoyl)phenylboronic acid; 4-(N-tert-Butylsulfamoyl)phenylboronic acid; 4-(tert-Butylaminosulfonyl)phenylboronic acid; 4-(tert-Butylsulfamoyl)benzeneboronic acid
EINECS	Contact for details

Quality Control

Every batch of 4-(tert-Butylaminosulphonyl)Benzeneboronic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with detailed specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.