Description

2',3',6'-Trifluoroacetophenone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms on the aromatic ring, which can dramatically influence the electronic properties, metabolic stability, and lipophilicity of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in display technologies.
• Organic Electronics: Employed in the synthesis of fluorinated organic semiconductors and charge-transport materials.
• Complex Ligand Preparation: Useful for creating fluorinated ligands in catalysis and material science.
• Advanced Material Research: Acts as a building block for polymers and coatings with specific surface properties.

Basic Information

Product Name	2',3',6'-Trifluoroacetophenone
CAS No.	208173-22-2
Molecular Formula	C8H5F3O
Molecular Weight	174.12 g/mol
Synonyms	1-(2,3,6-Trifluorophenyl)ethanone; 2,3,6-Trifluoroacetophenone; Ethanone, 1-(2,3,6-trifluorophenyl)-; α,α,α-Trifluoro-o-tolualdehyde (incorrect but common search term); 2,3,6-Trifluorophenyl methyl ketone; TFAP (abbreviation); Trifluoroacetylbenzene derivative
EINECS	Contact for details

Quality Control

Our 2',3',6'-Trifluoroacetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, reducing agents, and heat sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.