Description

2,3-Difluorobenzophenone is a high-purity fluorinated aromatic ketone building block of significant importance in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms on the benzophenone core, which allows for precise tuning of electronic properties and metabolic stability in target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitors and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the difluoro motif enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorine-containing compounds used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to improve thermal stability, chemical resistance, and optical properties.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a scaffold for constructing complex heterocycles in medicinal chemistry.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new fluorination chemistry and material science applications.

Basic Information

Product Name	2,3-Difluorobenzophenone
CAS No.	208173-20-0
Molecular Formula	C13H8F2O
Molecular Weight	218.20 g/mol
Synonyms	(2,3-Difluorophenyl)(phenyl)methanone; Benzophenone, 2,3-difluoro-; 2,3-Difluorobenzophenone; 2,3-Difluorodiphenylmethanone; 2,3-DFBP; α,2,3-Trifluorobenzophenone (incorrect but common misnomer)
EINECS	Contact for details

Quality Control

Our 2,3-Difluorobenzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.