Description

[Rh Cod (S)-Binap]Bf4, Rh 11.2% CAS NO 208118-82-5 is a high-purity, rhodium-based chiral catalyst complex, specifically a cationic rhodium(I) complex with (S)-BINAP and 1,5-cyclooctadiene (COD) ligands. This compound is a critical enabler for asymmetric hydrogenation and other enantioselective transformations, allowing for the production of single-isomer intermediates with high optical purity. It is an essential tool for pharmaceutical R&D, fine chemical synthesis, and advanced material science, where precise stereochemical control is paramount for product efficacy and performance.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of prochiral olefins, ketones, and imines to produce chiral alcohols and amines.
• Pharmaceutical Intermediate Synthesis: Key for manufacturing active pharmaceutical ingredients (APIs) requiring specific chirality, such as certain drug molecules for cardiovascular and central nervous system diseases.
• Fine Chemical Production: Used in the synthesis of high-value agrochemicals, flavors, and fragrances where stereochemistry impacts biological activity or scent profile.
• Academic and Industrial Research: A standard catalyst for methodology development in organic synthesis and process chemistry optimization.
• Chiral Ligand Screening: Serves as a precursor or benchmark in the development and evaluation of new chiral catalyst systems.

Basic Information

Product Name	[Rh Cod (S)-Binap]Bf4, Rh 11.2% CAS NO 208118-82-5
CAS No.	208118-82-5
Molecular Formula	C~44~H~40~BF~4~P~2~Rh • (Solvate)
Molecular Weight	Contact for details
Synonyms	(S)-(-)-1,1'-Binaphthalene-2,2'-diylbis[diphenylphosphine][(1,2,5,6-η)-1,5-cyclooctadiene]rhodium(1+) tetrafluoroborate; Rhodium(I)-(S)-BINAP-COD tetrafluoroborate; [(S)-BINAP)Rh(COD)]BF4; (S)-BINAP-Rh(COD)BF4; Rh-(S)-BINAP Catalyst; Chiral Rhodium(I) BINAP Complex; Asymmetric Hydrogenation Catalyst Rh(S)-BINAP
EINECS	Contact for details

Quality Control

Every batch of our [Rh Cod (S)-Binap]Bf4 catalyst is manufactured and tested under strict quality management systems. We ensure high catalytic activity and enantiomeric purity through comprehensive analytical techniques including NMR, HPLC, and elemental analysis. A Certificate of Analysis (COA) detailing Rhodium content, chiral purity, and solvent residues is provided with each shipment to guarantee consistency and performance for your critical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., argon or nitrogen) at 2-8°C or as specified on the label. This material is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Keep the container sealed in a dry and cool environment. For long-term storage, consider storage at -20°C.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline or amorphous solid
Identification (IR)	Conforms to structure
Rhodium Content	≈ 11.2 %
Purity (HPLC)	≥ 95.0%
Solvent Content (Residual)	≤ 5.0% (by NMR)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.