Description

α-Bromo-4-(Diethylamino)Acetophenone is a specialized brominated aromatic ketone derivative, serving as a crucial pharmaceutical intermediate and organic synthesis building block. Its molecular structure, featuring both a reactive α-bromo ketone moiety and a diethylamino group, makes it a versatile precursor for synthesizing more complex molecules. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those with amine or ketone functionalities.
• Organic Synthesis Reagent: Used in nucleophilic substitution and condensation reactions to introduce the 4-(diethylamino)acetophenone moiety into target molecules.
• Research & Development: Employed in medicinal chemistry for the discovery and development of new drug candidates and bioactive compounds.
• Fine Chemical Production: Intermediate in the manufacture of dyes, pigments, and advanced organic materials requiring specific optical or electronic properties.
• Chemical Biology Probes: Potential use in creating photoaffinity labels or other probes due to its reactive bromine atom and chromophore.

Basic Information

Item	Details
Product Name	α-Bromo-4-(Diethylamino)Acetophenone
CAS No.	207986-25-2
Molecular Formula	C₁₂H₁₆BrNO
Molecular Weight	270.17 g/mol
Synonyms	2-Bromo-1-[4-(diethylamino)phenyl]ethanone; ω-Bromo-4'-diethylaminoacetophenone; 4'-(Diethylamino)-2-bromoacetophenone; 2-Bromo-4'-(diethylamino)acetophenone; α-Bromo-4-diethylaminoacetophenone; p-(Diethylamino)-α-bromoacetophenone; 1-[4-(Diethylamino)phenyl]-2-bromoethan-1-one
EINECS	Contact for details

Quality Control

Our α-Bromo-4-(Diethylamino)Acetophenone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure it meets the high standards required for pharmaceutical and research applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.