Description

3'-Fluoro-5'-(Trifluoromethyl)Propiophenone is a high-value fluorinated aromatic ketone building block, essential for advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl substituents, is critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in CNS and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals that require specific electronic and steric properties.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a building block for electron-transport or host materials in display technologies.
• Fluorine Chemistry Studies: A valuable reference compound for academic and industrial research into structure-activity relationships (SAR) of fluorinated aromatics.

Basic Information

Product Name	3'-Fluoro-5'-(Trifluoromethyl)Propiophenone
CAS No.	207974-20-7
Molecular Formula	C10H8F4O
Molecular Weight	220.16 g/mol
Synonyms	1-[3-Fluoro-5-(trifluoromethyl)phenyl]propan-1-one; 3-Fluoro-5-(trifluoromethyl)propiophenone; 3'-Fluoro-α,α,α-trifluoro-3-methylpropiophenone; 3-Fluoro-5-trifluoromethylpropiophenone; Propiophenone, 3'-fluoro-5'-(trifluoromethyl)-; 1-(3-Fluoro-5-(trifluoromethyl)phenyl)-1-propanone
EINECS	Contact for details

Quality Control

Our 3'-Fluoro-5'-(Trifluoromethyl)Propiophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.