Description

2-Fluoro-4-(trifluoromethyl)benzophenone is a high-value fluorinated aromatic ketone building block, distinguished by its unique substitution pattern. This compound is critical for introducing specific steric and electronic properties into target molecules, enabling advanced material and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides and pesticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Incorporated as a monomer or cross-linking agent to create specialty polymers with enhanced thermal stability, chemical resistance, and specific optical properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to construct complex, fluorinated aromatic systems.
• Chemical Research & Development: Utilized in academic and industrial labs for methodological studies and the discovery of new reactions involving fluorinated aromatics.

Basic Information

Product Name	2-Fluoro-4-(trifluoromethyl)benzophenone
CAS No.	207974-08-1
Molecular Formula	C14H8F4O
Molecular Weight	268.21 g/mol
Synonyms	(2-Fluorophenyl)[4-(trifluoromethyl)phenyl]methanone; 2-Fluoro-4'-(trifluoromethyl)benzophenone; 4'-Trifluoromethyl-2-fluorobenzophenone; Benzophenone, 2-fluoro-4-(trifluoromethyl)-; Methanone, (2-fluorophenyl)[4-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-(trifluoromethyl)benzophenone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.