Description

2'-Fluoro-3'-(Trifluoromethyl)Acetophenone is a high-value fluorinated aromatic ketone building block, essential for introducing specific fluorine-containing motifs into complex molecular architectures. Its unique structure, featuring both fluorine and a trifluoromethyl group on the acetophenone core, makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs). This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluorine atoms improve metabolic stability and bioavailability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, contributing to improved performance and stability.
• Advanced Polymer Monomers: Employed in the creation of specialty polymers with specific chemical resistance and surface properties.
• Organic Synthesis & Catalysis Research: A versatile substrate for developing new fluorination methodologies and cross-coupling reactions in academic and industrial R&D.
• Fluorinated Ligand Preparation: Used to synthesize complex ligands for catalysis and material science applications.

Basic Information

Product Name	2'-Fluoro-3'-(Trifluoromethyl)Acetophenone
CAS No.	207853-63-2
Molecular Formula	C9H6F4O
Molecular Weight	206.14 g/mol
Synonyms	1-(2-Fluoro-3-(trifluoromethyl)phenyl)ethan-1-one; 2'-Fluoro-3'-trifluoromethylacetophenone; 1-Acetyl-2-fluoro-3-(trifluoromethyl)benzene; 2-Fluoro-α,α,α-trifluoro-m-acetophenone; 2-Fluoro-3-trifluoromethylacetophenone; m-Trifluoromethyl-2-fluoroacetophenone; Ethanone, 1-[2-fluoro-3-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 2'-Fluoro-3'-(Trifluoromethyl)Acetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.