Description

3-(2-Phenylethynyl)Benzoic Acid Ethyl Ester is a specialized organic building block featuring a conjugated ethynyl-phenyl system. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in advanced materials and pharmaceutical research. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for applications such as Suzuki coupling reactions and the synthesis of functionalized polymers or liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring conjugated aromatic systems.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or precursor for organic semiconductors, liquid crystals, and advanced polymers with specific optical or electronic properties.
• Cross-Coupling Reactions: An effective substrate in palladium-catalyzed reactions like Sonogashira, Suzuki, or Heck couplings to create complex biaryl and extended π-conjugated systems.
• Organic Synthesis Building Block: Provides a rigid, linear ethynyl linker for constructing molecular rods, ligands for catalysis, and other specialty organic compounds.

Basic Information

Product Name	3-(2-Phenylethynyl)Benzoic Acid Ethyl Ester
CAS No.	207845-32-7
Molecular Formula	C17H14O2
Molecular Weight	250.29 g/mol
Synonyms	Ethyl 3-(2-Phenylethynyl)benzoate; Benzoic acid, 3-(2-phenylethynyl)-, ethyl ester; 3-(Phenylethynyl)benzoic acid ethyl ester; Ethyl m-(phenylethynyl)benzoate; 3-Ethynylbenzoic acid ethyl ester phenyl derivative; NSC 797883; Aromatic acetylene ester intermediate
EINECS	Contact for details

Quality Control

Our 3-(2-Phenylethynyl)Benzoic Acid Ethyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.