Description

1-Piperazinecarboxylicacid,4-Borono-,1-Methylester(9Ci) CAS NO 207798-77-4 is a specialized boronic acid ester derivative of piperazine, serving as a crucial building block in modern synthetic chemistry. Its primary value lies in its dual functionality, where the boronic acid ester group enables Suzuki-Miyaura cross-coupling reactions, and the piperazine scaffold provides a versatile nitrogen-containing heterocycle. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the synthesis of complex molecules, active pharmaceutical ingredients (APIs), and novel materials requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its boronic ester functionality for carbon-carbon bond formation.
• Material Science Research: Serves as a precursor for creating functionalized polymers and organic frameworks with specific electronic or structural properties.
• Cross-Coupling Reactions: An essential reagent in palladium-catalyzed Suzuki-Miyaura cross-coupling reactions to form biaryl and other complex structures.
• Chemical Biology & Proteomics: Utilized as a molecular probe or linker in bioconjugation and target identification studies.
• Catalyst & Ligand Development: Acts as a starting material for synthesizing novel ligands and catalysts used in asymmetric synthesis.

Basic Information

Product Name	1-Piperazinecarboxylicacid,4-Borono-,1-Methylester(9Ci)
CAS No.	207798-77-4
Molecular Formula	C7H13BN2O3
Molecular Weight	184.00 g/mol
Synonyms	4-Borono-1-piperazinecarboxylic acid 1-methyl ester; Methyl 4-boronopiperazine-1-carboxylate; 1-Methyl 4-boronopiperazine-1-carboxylate; Piperazine-1-carboxylic acid, 4-borono-, methyl ester; 207798-77-4; Methyl (4-boronopiperazin-1-yl)formate
EINECS	Contact for details

Quality Control

Our 1-Piperazinecarboxylicacid,4-Borono-,1-Methylester(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our commitment to quality supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.