Description

4-(4-Formyl-Phenoxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its unique piperidine and formylphenoxy functional groups. This compound is a critical building block in modern organic synthesis, enabling the efficient construction of complex molecules with high selectivity and yield. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting neurological pathways.
• Organic Synthesis Building Block: Used in multi-step synthesis for constructing piperidine-containing scaffolds and other heterocyclic compounds.
• Medicinal Chemistry Research: Essential for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Custom Synthesis: Serves as a starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized fine chemicals.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	4-(4-Formyl-Phenoxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	207798-38-7
Molecular Formula	C17H23NO4
Molecular Weight	305.37 g/mol
Synonyms	1-Boc-4-(4-formylphenoxy)piperidine; tert-Butyl 4-(4-formylphenoxy)piperidine-1-carboxylate; 4-(4-Formylphenoxy)piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(4-formylphenoxy)piperidine; 4-Formylphenoxy-piperidine-1-carboxylic acid tert-butyl ester; N-Boc-4-(4-formylphenoxy)piperidine; Piperidine-1-carboxylic acid, 4-[(4-formylphenyl)oxy]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 4-(4-Formyl-Phenoxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.