Description

1-Pentanesulfonic Acid Sodium Salt Monohydrate is a high-purity sulfonate salt widely used as a key ion-pairing reagent in analytical chemistry. Its primary commercial value lies in its ability to enhance the separation and detection of hydrophobic compounds, particularly in reverse-phase liquid chromatography. This product is essential for analytical laboratories and manufacturers in the pharmaceutical, biotechnology, and chemical research sectors requiring precise and reproducible analytical methods.

Application

• Ion-Pairing Reagent for HPLC: Critical for the analysis of basic compounds, peptides, and pharmaceuticals using reverse-phase chromatography.
• Pharmaceutical Analysis: Used in the quality control and stability testing of active pharmaceutical ingredients (APIs) and finished drug products.
• Biomolecule Separation: Facilitates the separation and purification of complex biomolecules like oligonucleotides and proteins in research and development.
• Method Development: A standard reagent for developing and validating robust analytical methods in compliance with regulatory guidelines (e.g., ICH).
• Chemical Synthesis Intermediate: Serves as a building block or catalyst in specialized organic synthesis processes.
• Buffer Component: Used in the preparation of mobile phases to control pH and improve chromatographic peak shape.

Basic Information

Product Name	1-Pentanesulfonic Acid Sodium Salt Monohydrate
CAS No.	207605-40-1
Molecular Formula	C5H11NaO3S · H2O
Molecular Weight	192.20 g/mol (Monohydrate)
Synonyms	Sodium 1-Pentanesulfonate Monohydrate; Sodium Pentanesulfonate Monohydrate; 1-Pentanesulfonic Acid Sodium Salt; Pentanesulfonic Acid Sodium Salt; Sodium Pentylsulfonate; PIC B5 Reagent; Ion-Pair Reagent B5; IPS B5
EINECS	Contact for details

Quality Control

Our 1-Pentanesulfonic Acid Sodium Salt Monohydrate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including assay, identification, and impurity profiling, to ensure it meets the high-purity standards required for analytical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your methodological requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	7.0% - 10.0%
pH (5% Solution)	6.0 - 8.0
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Chromatographic Purity (HPLC)	Meets internal standard

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.