Description

Boronic Acid, B-2,1,3-Benzoxadiazol-4-Yl- is a specialized heterocyclic boronic acid derivative, serving as a crucial building block in modern synthetic chemistry. Its primary value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those containing benzoxadiazole scaffolds for therapeutic applications.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides requiring specific heterocyclic architectures.
• Material Science: Employed in the development of organic electronic materials, such as OLEDs and sensors, due to its conjugated system.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid pinacol ester precursor for palladium-catalyzed C-C bond formation.
• Chemical Biology & Proteomics: Acts as a handle for bioconjugation and the development of chemical probes and inhibitors.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Item	Detail
Product Name	Boronic Acid, B-2,1,3-Benzoxadiazol-4-Yl-
CAS No.	207279-32-1
Molecular Formula	C8H7BN2O3
Molecular Weight	189.96 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,1,3-benzoxadiazole; 2,1,3-Benzoxadiazol-4-ylboronic acid pinacol ester; 4-(Pinacolatoboryl)-2,1,3-benzoxadiazole; 4-Boronobenzofurazan pinacol ester; Benzofurazan-4-boronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzofurazan; B-(2,1,3-Benzoxadiazol-4-yl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our Boronic Acid, B-2,1,3-Benzoxadiazol-4-Yl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity suitable for sensitive cross-coupling reactions. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency, meeting the stringent requirements of R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.