Description

5-((Trimethylsilyl)Ethynyl)Thiophene-2-Carbaldehyde is a high-value organosilicon building block featuring a reactive aldehyde group and a protected acetylene moiety. This compound is essential for advanced organic synthesis, particularly in the construction of complex conjugated systems and heterocyclic frameworks. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and materials science sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Organic Electronic Materials: Serves as a precursor for conjugated polymers and small molecules used in OLEDs, OFETs, and organic photovoltaics.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides with tailored properties.
• Ligand and Catalyst Development: Employed in the synthesis of sophisticated ligands for transition metal catalysis and organocatalysis.
• Chemical Biology Probes: Useful for creating labeled compounds and molecular probes for biological target identification.
• Academic & Industrial R&D: A versatile building block for exploratory chemistry and the synthesis of complex thiophene derivatives.

Basic Information

Product Name	5-((Trimethylsilyl)Ethynyl)Thiophene-2-Carbaldehyde
CAS No.	206768-50-5
Molecular Formula	C10H14OSSi
Molecular Weight	210.37 g/mol
Synonyms	2-Formyl-5-((trimethylsilyl)ethynyl)thiophene; 5-(Trimethylsilylethynyl)thiophene-2-carboxaldehyde; 5-(Trimethylsilylethynyl)-2-thiophenecarboxaldehyde; 2-Thiophenecarboxaldehyde, 5-[(trimethylsilyl)ethynyl]-; 5-(Trimethylsilylethynyl)thiophene-2-carbaldehyde; 5-(TMS-ethynyl)thiophene-2-carbaldehyde
EINECS	Contact for details

Quality Control

Our 5-((Trimethylsilyl)Ethynyl)Thiophene-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Custom purity grades and analytical packages are available to meet specific research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to light brown solid or liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.