Description

2-Thiophenecarboxaldehyde, 5-Ethynyl- (9Ci) is a high-value, multi-functional heterocyclic building block characterized by its reactive aldehyde and terminal alkyne functional groups. This unique bifunctional structure makes it a critical intermediate for the synthesis of complex molecules, enabling advanced material and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing novel thiophene-based scaffolds, ligands, and polymers.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for constructing thiophene-containing heterocycles.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, where the thiophene moiety can impart specific biological activity.
• Material Science & Organic Electronics: A vital building block for creating conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and field-effect transistors (OFETs).
• Chemical Biology & Bioconjugation: The terminal alkyne group enables efficient "click chemistry" reactions (e.g., CuAAC) for labeling, tagging, and linking biomolecules or materials.
• Ligand & Catalyst Development: Employed in the design and synthesis of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: Essential for exploratory research in synthetic organic chemistry to develop new methodologies and complex molecular architectures.

Basic Information

Product Name	2-Thiophenecarboxaldehyde, 5-Ethynyl- (9Ci)
CAS No.	206768-21-0
Molecular Formula	C7H4OS
Molecular Weight	136.17 g/mol
Synonyms	5-Ethynyl-2-thiophenecarboxaldehyde; 5-Ethynylthiophene-2-carbaldehyde; 2-Formyl-5-ethynylthiophene; 5-Ethynyl-2-formylthiophene; 5-Ethynylthiophene-2-carboxaldehyde; 5-Ethynyl-2-thiophenecarbaldehyde
EINECS	Contact for details

Quality Control

Our 2-Thiophenecarboxaldehyde, 5-Ethynyl- (9Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support our clients with custom synthesis and purity grade options to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress and degradation.

Specification

Item	Specification
Appearance	Yellow to brown crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.