Description

2-Cyclopentene-1-Carboxylicacid,4-Hydroxy-1-Methyl-,Methylester,(1S,4S)- is a high-purity, chiral cyclopentene derivative that serves as a critical advanced intermediate in complex organic syntheses. Its defined stereochemistry and functional group array make it a valuable building block for constructing molecules with specific three-dimensional architectures. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for complex, stereospecific drug molecules.
• Asymmetric Synthesis: Utilized as a building block in catalytic asymmetric reactions to introduce the (1S,4S) stereocentre into target molecules.
• Fine Chemical Production: Serves as a precursor in the multi-step synthesis of specialty chemicals, agrochemicals, and performance materials.
• Academic & Industrial Research: Used in methodological studies and process chemistry development for novel synthetic routes.
• Ligand and Catalyst Development: Potential starting material for the synthesis of novel chiral ligands or organocatalysts.

Basic Information

Product Name	2-Cyclopentene-1-Carboxylicacid,4-Hydroxy-1-Methyl-,Methylester,(1S,4S)-
CAS No.	206755-02-4
Molecular Formula	C8H12O3
Molecular Weight	156.18 g/mol
Synonyms	(1S,4S)-4-Hydroxy-1-methyl-2-cyclopentene-1-carboxylic acid methyl ester; Methyl (1S,4S)-4-hydroxy-1-methyl-2-cyclopentene-1-carboxylate; (1S,4S)-Methyl 4-hydroxy-1-methyl-2-cyclopentene-1-carboxylate; (1S-cis)-4-Hydroxy-1-methyl-2-cyclopentene-1-carboxylic Acid Methyl Ester; Chiral cyclopentene ester; Optically active cyclopentene derivative
EINECS	Contact for details

Quality Control

Our production of this advanced chiral intermediate adheres to strict quality management systems. Every batch is characterized and tested to ensure identity, purity, and enantiomeric excess meet rigorous standards. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results from analytical methods including HPLC, GC, and chiral analysis. We support cGMP compliance for pharmaceutical applications and can provide documentation to meet audit requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.