Description

3-Chloro-3-(4-Fluorophenyl)Acrylonitrile is a high-value, halogenated acrylonitrile derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and fluoro substituents, makes it an essential intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with specific optical or electronic properties.
• Liquid Crystal & OLED Materials: A valuable synthon for creating advanced organic electronic materials due to its conjugated system and halogen atoms.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reactions in palladium-catalyzed cross-couplings and cycloadditions.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for the production of bespoke compounds and libraries for high-throughput screening.

Basic Information

Product Name	3-Chloro-3-(4-Fluorophenyl)Acrylonitrile
CAS No.	205984-77-6
Molecular Formula	C9H5ClFN
Molecular Weight	181.59 g/mol
Synonyms	(E/Z)-3-Chloro-3-(4-fluorophenyl)acrylonitrile; 3-Chloro-3-(p-fluorophenyl)acrylonitrile; 2-Chloro-2-(4-fluorophenyl)ethene-1-carbonitrile; 4-Fluoro-β-chlorocinnamonitrile; (4-Fluorophenyl)-2-chloro-2-propenenitrile; 3-Chloro-3-(4'-fluorophenyl)-2-propenenitrile; NSC 339063
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-3-(4-Fluorophenyl)Acrylonitrile is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.