Description

Cyclohexanecarboxaldehyde, 2-(Hydroxymethyl)-, cis- (9Ci) is a specialized chiral aldehyde building block of significant interest in advanced organic synthesis. Its unique structure, featuring both aldehyde and hydroxymethyl functional groups on a cis-configured cyclohexane ring, makes it a valuable precursor for constructing complex, stereodefined molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and fine chemical industries for applications such as asymmetric synthesis and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring a defined stereochemistry.
• Asymmetric Synthesis: Serves as a versatile starting material or chiral auxiliary in catalytic asymmetric reactions to create enantiomerically pure compounds.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, fragrances, and advanced materials where its specific stereochemistry imparts desired properties.
• Academic & Industrial Research: Employed in methodological development and exploratory chemistry to create novel molecular architectures and study stereochemical outcomes.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing novel chiral ligands and organocatalysts used in enantioselective transformations.

Basic Information

Product Name	Cyclohexanecarboxaldehyde, 2-(Hydroxymethyl)-, cis- (9Ci)
CAS No.	205873-97-8
Molecular Formula	C8H14O2
Molecular Weight	142.20 g/mol
Synonyms	cis-2-(Hydroxymethyl)cyclohexanecarboxaldehyde; (1R,2S)-rel-2-(Hydroxymethyl)cyclohexanecarbaldehyde; cis-2-Hydroxymethyl-cyclohexanecarbaldehyde; 2-Hydroxymethyl-cyclohexanecarboxaldehyde, cis-; Cyclohexanecarboxaldehyde, 2-(hydroxymethyl)-, (1R,2S)-rel-; (1R,2S)-2-(Hydroxymethyl)cyclohexane-1-carbaldehyde
EINECS	Contact for details

Quality Control

Our Cyclohexanecarboxaldehyde, 2-(Hydroxymethyl)-, cis- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). For long-term storage, consider storing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% cis-isomer
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.