Description

Cyclobutanecarboxaldehyde, 2-Phenyl- (9Ci) CAS NO 205679-31-8 is a specialized organic building block featuring a cyclobutane ring substituted with a phenyl group and an aldehyde functionality. This unique structure makes it a valuable intermediate for synthesizing complex molecules in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients, fragrances, and materials science. The compound's reactivity profile offers strategic pathways for constructing constrained ring systems and introducing specific chiral centers.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for creating conformationally restricted analogs and complex heterocycles.
• Agrochemical Synthesis: Used in the preparation of advanced active ingredients for crop protection, leveraging its aldehyde group for further chemical transformations.
• Fragrance & Flavor Chemistry: Serves as a precursor for synthesizing unique aroma chemicals with specific olfactory properties derived from its phenyl-substituted cyclobutane core.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials where the rigid cyclobutane structure can impart desired physical properties.
• Academic & Industrial R&D: A versatile building block for methodological studies in organic synthesis, including cycloaddition reactions and catalytic asymmetric transformations.
• Fine Chemical Production: Used in the multi-step synthesis of complex, high-value fine chemicals for various industrial applications.

Basic Information

Item	Detail
Product Name	Cyclobutanecarboxaldehyde, 2-Phenyl- (9Ci)
CAS No.	205679-31-8
Molecular Formula	C11H12O
Molecular Weight	160.21 g/mol
Synonyms	2-Phenylcyclobutanecarboxaldehyde; 2-Phenylcyclobutanecarbaldehyde; (2-Phenylcyclobutyl)methanal; α-Phenylcyclobutanemethanol, aldehyde; Cyclobutanecarboxaldehyde, 2-phenyl-; 2-Phenyl-1-cyclobutanecarboxaldehyde
EINECS	Contact for details

Quality Control

Our Cyclobutanecarboxaldehyde, 2-Phenyl- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system is designed to meet the stringent requirements of pharmaceutical and R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from heat, sparks, and open flame. Due to its sensitivity, allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.