Description

Cethromycin CAS NO 205110-48-1 is a semi-synthetic ketolide antibiotic derived from erythromycin. This advanced macrolide compound is specifically designed to combat respiratory tract infections caused by multidrug-resistant bacteria, including macrolide-resistant strains. It is a critical active pharmaceutical ingredient (API) for pharmaceutical R&D and manufacturing, targeting the development of next-generation antibacterial therapies for global healthcare markets.

Application

• Pharmaceutical API: Primary use as the active ingredient in the formulation of antibacterial drugs.
• Respiratory Infection Treatment: Development of therapeutics for community-acquired pneumonia (CAP), acute bacterial exacerbations of chronic bronchitis, and other lower respiratory tract infections.
• Antibacterial Research: A key reference standard and investigational compound in microbiological and pharmacological research against resistant pathogens like Streptococcus pneumoniae and Haemophilus influenzae.
• Drug Discovery & Development: Used in preclinical and clinical studies to explore new treatment regimens and combination therapies.
• Veterinary Medicine: Potential application in developing antibacterial treatments for animal health.

Basic Information

Product Name	Cethromycin
CAS No.	205110-48-1
Molecular Formula	C34H65NO9
Molecular Weight	631.89 g/mol
Synonyms	ABT-773; A-195773; Ketek; Cethromycinum; (3R,4S,5S,6R,7R,9R,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-12,13-dihydroxy-4-{[(2R,3R,4S,6R)-3-hydroxy-6-methyl-4-(propionylamino)oxan-2-yl]oxy}-7-methoxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione
EINECS	Contact for details

Quality Control

Our Cethromycin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identification by IR and NMR, and stringent control of related substances and residual solvents to ensure compliance with pharmaceutical-grade standards. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and regulatory support for your projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Water Content (KF)	≤2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.