Description

5-Bromo-1,3-Dichloro-2-Methylbenzene is a halogenated aromatic compound that serves as a versatile and valuable building block in advanced organic synthesis. Its molecular structure, featuring bromine and chlorine substituents on a methylbenzene core, makes it a critical intermediate for constructing complex molecules. This compound is primarily utilized by research institutions and chemical manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where its halogenated structure contributes to biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig couplings to form complex biaryl structures.
• Chemical Library Development: Employed in high-throughput and combinatorial chemistry for generating diverse compound libraries for drug discovery screening.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing specialized halogenated dyes and organic pigments.

Basic Information

Product Name	5-Bromo-1,3-Dichloro-2-Methylbenzene
CAS No.	204930-37-0
Molecular Formula	C7H5BrCl2
Molecular Weight	239.93 g/mol
Synonyms	1-Bromo-3,5-dichloro-2-methylbenzene; 2-Methyl-1,3-dichloro-5-bromobenzene; 3,5-Dichloro-2-methylbromobenzene; 5-Bromo-1,3-dichloro-2-methyl-benzene; Benzene, 5-bromo-1,3-dichloro-2-methyl-; 2-Methyl-3,5-dichlorobromobenzene
EINECS	Contact for details

Quality Control

Our 5-Bromo-1,3-Dichloro-2-Methylbenzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.